A new drug for thyroid eye disease is said to have ‘promising’ results in clinical trials. The symptoms of Grave’s eye disease, such as red, irritable, and bulging eyes, diminish the quality of life of any person who has it. Fortunately, a new treatment for thyroid eye disease is currently undergoing clinical trials under the funding of River Vision Development Corporation. Read more about the clinical trial in this article from Optometry Today.
Promising Thyroid Eye Disease Treatment Under Clinical Trials
Researchers examined the effect of teprotumumab, a monoclonal antibody shown to inhibit IGF-1 function that was originally developed as a cancer drug.
At the end of the trial, 69% of patients had reduced eye bulging and reported increased quality of life, compared to 20% in the placebo group.
The most common side effect after treatment with the drug was nausea, while some patients with diabetes experienced hyperglycemia. This side effect was addressed by adjusting diabetes medication.
Teprotumumab shows promise for thyroid-associated ophthalmopathy https://t.co/DAbtNdB1eg
— AAO (@aao_ophth) June 2, 2017
The clinical trial compared the effects of teprotumumab and placebo. The placebo group didn’t have fast and effective results, unlike the teprotumumab. The results of the teprotumumab drug were promising enough for River Vision to discuss its production.
— U-M KelloggEyeCenter (@UMKelloggEye) May 25, 2017
This New Thyroid Eye Disease Drug Can Remove Bulging
The biggest symptom a person with Grave’s eye disease suffers are bulging eyes. Hyperthyroidism causes the tissues and muscles behind the eyes to become swollen. One of the main effects of the teprotumumab drug is the reduction of proptosis in the patients.
Teprotumumab Can Relieve Symptoms of Thyroid Eye Disease
Thyroid eye disease symptoms greatly affect the quality of life for those who have it. This teprotumumab drug successfully lessened the bulging of the eyes in the clinical trials. Once approved, this new thyroid eye disease drug will be recommended to relieve symptoms of thyroid eye disease.
Results of clinical trial with teprotumumab published in NEJM offer hope to patients with thyroid eye disease https://t.co/nU8ScgJoSF
— Judith Taylor (@Endo_Editor) May 10, 2017
Watch this video by MedRewind to know more eye signs of the Grave’s eye disease!
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